Rimonabant Offers Modest Weight Loss
"Rimonabant is a selective cannabinoid-1 receptor antagonist that is currently undergoing phase III trials to investigate whether it can help obese people lose weight. A review of the early research shows that it can produce a 5% reduction in weight after one year.
The increasing worldwide prevalence of obesity is creating a growing demand for effective treatments. One possible option is rimonabant. Cochrane Review Authors analysed data from four randomized controlled studies in which people were either given 20 mg rimonabant, 5 mg rimonabant or a placebo. At the same time they all followed a low calorie diet. Each of the trials ran for 1 year.
Over the year, people taking 20 mg rimonabant lost 4.9 kg more than those given the placebo. Those taking 5 mg only lost 1.3 kg more when compared with placebo.
Taking the higher dose of 20 mg rimonabant did, however, cause significantly more adverse effects, which may account for the fact that 40% of people overall dropped out of the trials early.
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1 Comments:
Child obesity is one factor that is often overlooked. But the fact of the matter is that it is quite a serious issue. Whether or the diet pills like phentermine can be of use for child obesity is a much debated issue. Though phentermine has been banned there are other weight loss drugs in the market. Most of them are deemed to be unfit to be administered to children. Even drugs like phentremine that can be had without prescription are not advisable to be prescribed for child obesity.
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